This group comprises all hormonal preparations for systemic use, except:
- Insulins, see A10.
- Anabolic steroids, see A14.
- Catecholamines, see C01C and R03C.
- Sex hormones, see G03.
- Sex hormones used in treatment of neoplastic diseases, see L02.
- Metreleptin used for treatment of complications of leptin deficiency in patients with generalised lipodystrophy is classified in A16AA.

This group comprises hypothalamic hormones; extracts, purified natural hormones and synthetic analogues.
Hypothalamic hormones used as diagnostic agents for pituitary function are classified in V04CD.