| C - Cardiovascular System | This group comprises substances used for the treatment of cardiovascular conditions.
Drugs used for the treatment of hypertension are classified in C02 - Antihypertensives, C03 - Diuretics, C07 - Beta blocking agents, C08 - Calcium channel blockers, and C09 - Agents acting on the renin-angiotensin system. For the classification of combination products of antihypertensives from different ATC groups, the following ranking should be used, from higher to lower precedence: C09, C07, C08, and C03.
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| | C02 - Antihypertensives | See also C03 - Diuretics, C07 - Beta blocking agents, C08 - Calcium channel blockers and C09 - Agents acting on the renin-angiotensin system.
Antihypertensives are mainly classified at 3rd levels according to the mechanism of action. Most headings are self-explanatory:
C02A Antiadrenergic agents, centrally acting
C02B Antiadrenergic agents, ganglion-blocking
C02C Antiadrenergic agents, peripherally acting
C02D Arteriolar smooth muscle, agents acting on
C02K Other antihypertensives
C02L Antihypertensives and diuretics in combination
C02N Combinations of antihypertensives in ATC gr. C02
| The oral DDDs are based on the average doses needed to reduce the blood pressure to a normal level in patients with mild-moderate hypertension.
Parenteral DDDs are based on dosages used for the treatment of hypertensive crises and are based on the content of the active ingredient pr. vial (ampoule).
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| | C02A - Antiadrenergic Agents, Centrally Acting | | |
| | C02AB - Methyldopa | Combinations with diuretics, see C02LB - Methyldopa and diuretics in combination.
Combinations with Rauwolfia alkaloids and diuretics, see C02LA - Rauwolfia alkaloids and diuretics in combination.
| Different DDDs have been established for the various stereoiso-meric forms of methyldopa, because of different potency.
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| | C02AB01 - Methyldopa (Levorotatory) | | Dose | Route of administration | Note |
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| | O | | | | P | |
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