| R - Respiratory System | Inhaled antiinfectives are classified in ATC group J - Antiinfectives for systemic use.
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| | R05 - Cough and Cold Preparations | This group comprises a large number of preparations, most of which are combined preparations.
Cold preparations containing therapeutic levels of antiinfectives should be classified in ATC group J - Antiinfectives for systemic use.
Cold preparations with therapeutic levels of analgesics/anti-inflammatory agents should be classified in the respective N02/M01 groups.
Cold preparations with both antiinfectives and analgesics should be classified in ATC group J - Antiinfectives for systemic use.
Cold preparations with minimal amounts of analgesics are classified in R05X - Other cold preparations.
See also R01 - Nasal preparations, R02 - Throat preparations, and
R03D - Other systemic drugs for obstructive airway diseases.
| Fixed DDDs are assigned for combinations. These DDDs are based on an average dose regimen of three times daily, and dosages in the upper area of the recommended dose ranges are chosen. The strengths of the various components are not taken into consideration. E.g. 6 UD (= 30 ml) is the fixed DDD for products where the recommended dose is 5-10 ml each time administered.
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| | R05D - Cough Suppressants, Excl. Combinations with Expectorants | Combined preparations are classified at separate 5th levels using the code number 20 (R05DA20 and R05DB20). These may also contain bronchodilating agents, antihistamines etc.
Combinations with expectorants, see R05F.
Combinations with xanthines, see R03DA.
Preparations, which contain small amounts of herbal extracts, menthol etc., are not regarded as combined preparations.
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| | R05DA - Opium Alkaloids and Derivatives | Plain codeine, also when used as an analgesic, is classified in this group.
Plain dihydrocodeine products, also used as cough suppressants, are classified in N02AA.
All combined products of opium alkaloids and derivatives, are classified in R05DA20.
Combinations with analgesics are classified in N02.
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